ncRNA name | HIF-1α siRNA |
ncRNA Category | siRNA |
Disease name | age-related macular degeneration (AMD) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cells |
Methods | siRNA transfection, immunohistochemistry, Northern blot, qPCR, Western blot |
Expression pattern | associated |
Functional description | Using siRNA against HIF-1alpha, the hypoxia-mediated increase of CTGF and PAI-1 was inhibited. |
PubMed ID | 19118548 |
Year | 2009 |
Title | Hypoxia/reoxygenation induces CTGF and PAI-1 in cultured human retinal pigment epithelium cells. |
Drug-related ncRNA | NO |
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